Joanna Trylska

Molecular machines are nanoscale systems performing specific functions. Living cells build thousands of custom-designed macromolecular complexes such as the ribosome, transcriptional machinery, motors and transporters, all of which work in a precisely organized manner. Knowledge of their properties is of crucial importance in bionanotechnology.

Joanna Trylska’s group explores the function, dynamics, and physical properties of macromolecular assemblies to understand their activities in the living cell. The main object of her studies is the ribosome – the molecular complex responsible for protein synthesis. Other systems include viruses and chromatine. Studies involve the effects of macromolecular crowding in the cell on the functioning of the machines. The ultimate goal is to find new antibiotics inhibiting the function of bacterial ribosomes. More information can be found at or via e-mail: joanna(at)